A day’s pruning can stave off inflammation and osteoporosis

An estimated 13.6 million people in the US over the age of 50 will have osteoporosis – a loss of bone strength due to decreased bone mineral density – by 2030.

Osteoporosis increases the risk of fractures, especially in the elderly.

People going through menopause have lower levels of estrogen, which causes an increase in inflammation in the body, which can also contribute to bone loss.

Previous research has shown that extracts of polyphenols – plant compounds that act as antioxidants and reduce inflammation – in prunes promote reduced levels of oxidative stress and inflammation in a type of bone cell called osteoclasts.

In a new study, researchers from the Program on Biomedical and Integrative Physiology and the Department of Nutritional Sciences and Kinesiology at Pennsylvania State University explored the impact of prunes on bone health after menopause. terrible.

Postmenopausal women with a defined low bone mineral density score – a marker of osteoporosis – were divided into three groups:

  • One group ate 50 grams (g) of prunes (about six prunes) per day for 12 months.
  • The second group ate 100 g of prunes (about 12 prunes) per day for 12 months.
  • A control group did not eat prunes.
  • The team looked at blood samples taken from all the volunteers before and after the trial and found a significant reduction in inflammatory markers in both groups that ate the prunes compared with the controls.

    “Our findings suggest that consuming 6 to 12 prunes per day can reduce inflammatory mediators that may contribute to bone loss in postmenopausal women. Therefore, prunes have could be a promising nutritional intervention to block the proliferation of inflammatory mediators commonly observed in aging,” Janhavi Damani, MS, first author of the study said.

    Source: Eurekalert

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